{"id":11371,"date":"2023-01-06T20:10:33","date_gmt":"2016-10-03T15:10:33","guid":{"rendered":"https:\/\/www.shehuifa.com\/note\/?p=701"},"modified":"2025-11-13T13:56:23","modified_gmt":"2025-11-13T05:56:23","slug":"%e9%80%82%e8%80%85%e7%94%9f%e5%ad%98-%e5%a1%94%e6%96%af%e6%9b%bc%e5%b0%bc%e4%ba%9a%e6%81%b6%e9%ad%94%e7%9a%84%e8%bf%9b%e5%8c%96%e5%8f%8d%e5%ba%94","status":"publish","type":"post","link":"https:\/\/start.shehuifa.com\/?p=11371","title":{"rendered":"\u9002\u8005\u751f\u5b58\u2013 \u5854\u65af\u66fc\u5c3c\u4e9a\u6076\u9b54\u7684\u8fdb\u5316\u53cd\u5e94"},"content":{"rendered":"

\u6587\/\u97e6\u6587\u66e6<\/p>\n

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\u7531\u4e8e\u5a01\u5ec9\u5c71\u56fd\u5bb6\u516c\u56ed\u6709\u4e30\u5bcc\u7684\u91ce\u751f\u52a8\u7269\uff0c\u8377\u5170\u6444\u5f71\u5e08\u5df4\u65af\u5f88\u559c\u6b22\u5728\u90a3\u91cc\u62cd\u6444\uff0c\u800c\u62cd\u6444\u6076\u9b54\u662f\u4ed6\u7684\u5174\u8da3\u30021996 \u5e74\u7684\u67d0\u4e00\u5929\uff0c\u4ed6\u5982\u5e38\u7684\u67b6\u597d\u5e10\u7bf7\uff0c\u5e76\u7528\u4e0d\u540c\u98df\u7269\u5f15\u8bf1\u6076\u9b54\u6765\u4e34\uff0c\u597d\u8ba9\u4ed6\u80fd\u591a\u62cd\u51e0\u5f20\u76f8\u7247\u3002\u7ec8\u4e8e\u6709\u4e00\u523b\u88ab\u4ed6\u7b49\u5230\u4e86\uff0c\u53ef\u662f\u8fd9\u4e00\u53ea\u6076\u9b54\u7adf\u7136\u8ba9\u4ed6\u770b\u5230\u53d1\u5446\uff0c\u5df4\u65af\u8fde\u5fd9\u62cd\u4e0b\u7167\u7247\uff0c\u5e76\u628a\u7167\u7247\u9001\u5230\u5854\u65af\u66fc\u5c3c\u4e9a\u7684\u81ea\u7136\u4fdd\u80b2\u90e8\u95e8\u7ed9\u90a3\u91cc\u7684\u52a8\u7269\u5b66\u5bb6\u770b\uff0c\u4f46\u6ca1\u6709\u4e00\u4e2a\u91ce\u751f\u52a8\u7269\u4e13\u5bb6\u77e5\u9053\u53d1\u751f\u4ec0\u4e48\u4e8b\u60c5\u3002<\/p>\n

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\u7269\u7ade\u5929\u62e9\uff0c\u4fbf\u662f\u8fbe\u5c14\u6587\u8fdb\u5316\u8bba\u7684\u5176\u4e2d\u4e00\u4e2a\u91cd\u8981\u57fa\u7840\u3002<\/p><\/blockquote>\n

\u6700\u8fd1\u79d1\u5b66\u5bb6\u4ece\u5854\u65af\u66fc\u5c3c\u4e9a\u4e09\u4e2a\u4e0d\u540c\u5730\u65b9\u7684\u6076\u9b54\u627e\u5230\u63a5\u8fd1\u4e09\u767e\u53ea\u6ca1\u6709\u611f\u67d3\u9762\u90e8\u80bf\u7624\u75c5\u7684\u6076\u9b54\u548c\u521a\u5f00\u59cb\u7684\u53d1\u75c5\u7684\u6076\u9b54DNA [2]<\/sup>\u3002\u57fa\u56e0\u56fe\u8c31\u5206\u6790\u663e\u793a\u4e24\u4e2a\u5730\u533a\u5bf9\u8fd9\u4e2a\u75be\u75c5\u6709\u5f3a\u70c8\u7684\u9009\u62e9\u6027(selection)\uff0c\u800c\u4e24\u4e2a\u5730\u533a\u5f53\u4e2d\u7684\u4e94\u4e2a\u57fa\u56e0\uff0c\u5305\u62ecCD146\u3001 CD90 \u3001 CBL2 \u3001 USP2\u548cMRT2\u90fd\u4e0e\u514d\u75ab\u529f\u80fd\u548c\u764c\u75c7\u98ce\u9669\u6709\u5173\u3002\u900f\u8fc7\u7edf\u8ba1\u5b66\u5206\u6790\uff0c\u5728\u51e0\u4ee3\u7684\u6076\u9b54\u5df2\u5bf9\u9762\u90e8\u80bf\u7624\u75c5\u6709\u5f88\u5927\u7684\u57fa\u56e0\u7ec4\u53cd\u5e94(genomic response) \uff0c\u4e5f\u5373\u662f\u8bf4\uff0c\u6076\u9b54\u7684\u514d\u75ab\u7cfb\u7edf\u53ef\u80fd\u5df2\u8fdb\u5316\u5e76\u9002\u5e94\u8fd9\u4e2a\u6050\u5e03\u7684\u75be\u75c5\u3002<\/p>\n

\u6076\u9b54\u5bf9\u9762\u90e8\u80bf\u7624\u75c5\u7684\u8fdb\u5316\u53cd\u5e94\u5bf9\u8fd9\u4e2a\u7269\u79cd\u5f97\u4ee5\u7ee7\u7eed\u751f\u5b58\u6216\u6709\u4e00\u70b9\u5e0c\u671b\u3002\u5854\u65af\u66fc\u5c3c\u4e9a\u5f53\u5c40\u5df2\u68c0\u67e5\u5e76\u6311\u9009\u4e00\u5b9a\u6570\u91cf\u6ca1\u6709\u75c5\u53d8\u7684\u6076\u9b54\uff0c\u5e76\u628a\u5b83\u4eec\u5b89\u7f6e\u5728\u540d\u53ebMaria Island\u5c0f\u5c9b\u548cForestier\u534a\u5c9b\u4e0a[3]<\/sup>\uff0c\u5e0c\u671b\u5854\u65af\u66fc\u5c3c\u4e9a\u6076\u9b54\u8fd9\u4e2a\u7269\u79cd\u4e0d\u518d\u53d7\u8fd9\u4e2a\u75be\u75c5\u4f24\u5bb3\u5e76\u5f97\u4ee5\u7ee7\u7eed\u7e41\u6b96\u3002\u800c\u6682\u65f6\u6ca1\u6709\u8bc1\u636e\u663e\u793a\u6076\u9b54\u7684\u80bf\u7624\u7ec6\u80de\u53ef\u4ee5\u4f20\u5230\u5176\u4ed6\u52a8\u7269\u53ca\u4eba\u7c7b\u3002<\/p>\n

 <\/p>\n

\u53c2\u8003\u6587\u7ae0:<\/p>\n

    \n
  1. Grueber et al. (2015) Genomic insights into a contagious cancer in Tasmanian devils. \u00a0Trends in Genetics.<\/em> \u00a0DOI: 10.1016\/j.tig.2015.05.001<\/a><\/li>\n
  2. Epstein B et al (2016)Rapid evolutionary response to a transmissible cancer in Tasmanian devils.\u00a0 Nature Communications.<\/em> \u00a0DOI: 10.1038\/ncomms12684<\/a><\/li>\n
  3. Save the Tasmanian Devil<\/a><\/li>\n<\/ol>\n

    \u4f5c\u8005\u7b80\u4ecb\uff1a\u97e6\u6587\u66e6\uff0c\u82f1\u56fd\u725b\u6d25\u5927\u5b66\u533b\u5b66\u79d1\u5b66\u535a\u58eb\u6bd5\u4e1a\u3002\u784f\u7a76\u5174\u8da3\u4e3a\u764c\u75c7\u75c5\u53d8\u53ca\u6d4b\u8bd5\u3001\u5e72\u7ec6\u80de\u4ee5\u53ca\u518d\u751f\u533b\u5b66\u784f\u7a76\u7b49\u3002\u559c\u6b22\u751f\u547d\u79d1\u5b66\uff0c\u5e76\u5e0c\u671b\u628a\u751f\u7269\u79d1\u6280\u8d44\u8baf\u4ece\u8c61\u7259\u5854?\u5e26\u7ed9\u666e\u7f57\u5927\u4f17\u3002<\/p>\n

    \u539f\u6587\u520a\u4e8e\u4f5c\u8005\u535a\u5ba2<\/a>
    \n<\/small><\/p>\n","protected":false},"excerpt":{"rendered":"

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